Mathematical modeling and optimization of intratumor drug transport

DOI10.1007/s10559-007-0113-zzbMath1190.49005OpenAlexW2028420721MaRDI QIDQ941205

Yu. N. Onopchuk, N. I. Lyashko, D. A. Klyushin

Publication date: 4 September 2008

Published in: Cybernetics and Systems Analysis (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s10559-007-0113-z

zbMATH Keywords

optimal controlmathematical modeltumorpharmacological drug distributionpseudohyperbolic problem

Mathematics Subject Classification ID

Medical applications (general) (92C50) Existence theories for optimal control problems involving partial differential equations (49J20) Pseudohyperbolic equations (35L82)

Related Items (6)

Mathematical model of interaction of a symmetric top with an axially symmetric external field ⋮ Generalized optimization of processes of drug transport in tumors ⋮ Modeling the dynamics of a monocyclic cell aggregation system ⋮ Modeling the dynamics of age-structured polycyclic population of biological cells on the parameterized set of algebraic functions ⋮ Optimal control of drug delivery from microneedle systems ⋮ An analog of the Galerkin method in problems of drug delivery in biological tissues

Cites Work

• Trajectory and final controllability in hyperbolic and pseudohyperbolic systems with generalized actions
• Mathematical modelling of drug transport in tumour multicell spheroids and monolayer cultures

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