Optimizing design of two-stage experiments for transcriptional profiling

DOI10.1016/J.CSDA.2008.03.032MaRDI QIDQ961323zbMATH OpenOpenAlexWikidataFDO

Authors Juan P. Steibel, Guilherme J. M. Rosa, Robert J. Tempelman

Publication date 30 March 2010

Published in Computational Statistics and Data Analysis (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.csda.2008.03.032

Mathematics Subject Classification ID

Computational methods for problems pertaining to statistics (62-08) Applications of statistics to biology and medical sciences; meta analysis (62P10)

Recommendations

• Optimal designs for 2-color microarray experiments
• Design Considerations for Efficient and Effective Microarray Studies
• Comparison of various statistical methods for identifying differential gene expression in replicated microarray data
• COMPARISON OF DIFFERENT METHODOLOGIES TO IDENTIFY DIFFERENTIALLY EXPRESSED GENES IN TWO-SAMPLE cDNA MICROARRAYS
• Multicriteria gene screening for analysis of differential expression with DNA microarrays

Cites work

• A Direct Approach to False Discovery Rates
• Optimal two-stage genome-wide association designs based on false discovery rate
• Power and sample size estimation in high dimensional biology
• Two-stage designs for gene-disease association studies
• Two-Stage Designs for Gene-Disease Association Studies with Sample Size Constraints

Cited in

(2)

• Effect of adding fold-change criteria to significance testing of microarray data
• Editorial: Statistical genetics \& statistical genomics: where biology, epistemology, statistics, and computation collide

Describes a project that uses

Uses Software

• PowerAtlas

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