Bayesian testing of many hypotheses \(\times \) many genes: a study of sleep apnea

DOI10.1214/09-AOAS241zbMath1196.62140arXiv0903.0201MaRDI QIDQ985026

Shane T. Jensen, Dylan S. Small, Ibrahim Erkan, Erna S. Arnardottir

Publication date: 20 July 2010

Published in: The Annals of Applied Statistics (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/0903.0201

zbMATH Keywords

multiple comparisons; Bayesian hypothesis testing; hierarchical models; FDR control

Mathematics Subject Classification ID

62P10: Applications of statistics to biology and medical sciences; meta analysis

62F15: Bayesian inference

92C50: Medical applications (general)

62J15: Paired and multiple comparisons; multiple testing

Related Items

Gamma-based clustering via ordered means with application to gene-expression analysis, The importance of distinct modeling strategies for gene and gene-specific treatment effects in hierarchical models for microarray data, BOPA: A Bayesian hierarchical model for outlier expression detection

Uses Software

• gcrma

Cites Work

• Stochastic Relaxation, Gibbs Distributions, and the Bayesian Restoration of Images
• Linear Models and Empirical Bayes Methods for Assessing Differential Expression in Microarray Experiments
• A Model-Based Background Adjustment for Oligonucleotide Expression Arrays
• A Unified Approach for Simultaneous Gene Clustering and Differential Expression Identification
• Statistical significance for genomewide studies
• Bayesian Robust Inference for Differential Gene Expression in Microarrays with Multiple Samples
• Exploration, normalization, and summaries of high density oligonucleotide array probe level data
• Detecting differential gene expression with a semiparametric hierarchical mixture method
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