RARtrials
Some response-adaptive randomization methods commonly found in literature are included in this package. These methods include the randomized play-the-winner rule for binary endpoint (Wei and Durham (1978) <doi:10.2307/2286290>), the doubly adaptive biased coin design with minimal variance strategy for binary endpoint (Atkinson and Biswas (2013) <doi:10.1201/b16101>, Rosenberger and Lachin (2015) <doi:10.1002/9781118742112>) and maximal power strategy targeting Neyman allocation for binary endpoint (Tymofyeyev, Rosenberger, and Hu (2007) <doi:10.1198/016214506000000906>) and RSIHR allocation with each letter representing the first character of the names of the individuals who first proposed this rule (Youngsook and Hu (2010) <doi:10.1198/sbr.2009.0056>, Bello and Sabo (2016) <doi:10.1080/00949655.2015.1114116>), A-optimal Allocation for continuous endpoint (Sverdlov and Rosenberger (2013) <doi:10.1080/15598608.2013.783726>), Aa-optimal Allocation for continuous endpoint (Sverdlov and Rosenberger (2013) <doi:10.1080/15598608.2013.783726>), generalized RSIHR allocation for continuous endpoint (Atkinson and Biswas (2013) <doi:10.1201/b16101>), Bayesian response-adaptive randomization with a control group using the Thall \& Wathen method for binary and continuous endpoints (Thall and Wathen (2007) <doi:10.1016/j.ejca.2007.01.006>) and the forward-looking Gittins index rule for binary and continuous endpoints (Villar, Wason, and Bowden (2015) <doi:10.1111/biom.12337>, Williamson and Villar (2019) <doi:10.1111/biom.13119>).
- A response-adaptive randomization procedure for multi-armed clinical trials with normally distributed outcomes
- Implementing Optimal Allocation in Sequential Binary Response Experiments
- On recent advances in optimal allocation designs in clinical trials
- Optimal Adaptive Designs for Binary Response Trials With Three Treatments
- Outcome-adaptive allocation with natural lead-in for three-group trials with binary outcomes
- Practical Bayesian adaptive randomisation in clinical trials
- Randomised Response-Adaptive Designs in Clinical Trials
- Randomization in clinical trials. Theory and practice
- Response-adaptive randomization for multi-arm clinical trials using the forward looking Gittins index rule
- The Randomized Play-the-Winner Rule in Medical Trials
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