rabhit

MaRDI QIDQ77339CRANFDO

Authors Ayelet Peres, Gur Yaari, Moriah Gidoni

Last update 24 July 2026

Copyright license Creative Commons Attribution-ShareAlike 4.0 International

Software version identifier 0.2.5, PACKAGES.rds, 0.1.0.0, 0.1.1, 0.1.4, 0.1.5, 0.2.0, 0.2.1, 0.2.4, 0.4.0

Description

Infers V-D-J (Variable-Diversity-Joining) haplotypes and gene deletions from AIRR-seq (Adaptive Immune Receptor Repertoire sequencing) data for Ig (Immunoglobulin) and TR (T cell Receptor) chains, based on J (Joining), D (Diversity), or V (Variable) genes as anchor, by adapting a Bayesian framework. It also calculates a Bayes factor, a number that indicates the certainty level of the inference, for each haplotyped gene. Citation: Gidoni, et al (2019) <doi:10.1038/s41467-019-08489-3>. Peres and Gidoni, et al (2019) <doi:10.1093/bioinformatics/btz481>.

Cites work

• Mosaic deletion patterns of the human antibody heavy chain gene locus shown by Bayesian haplotyping
• RAbHIT: R Antibody Haplotype Inference Tool

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