ratesci
Computes confidence intervals for binomial or Poisson rates and their differences or ratios. Including the rate (or risk) difference ('RD') or rate ratio (or relative risk, 'RR') for binomial proportions or Poisson rates, and odds ratio ('OR', binomial only). Also confidence intervals for RD, RR or OR for paired binomial data, and estimation of a proportion from clustered binomial data. Includes skewness-corrected asymptotic score ('SCAS') methods, which have been developed in Laud (2017) <doi:10.1002/pst.1813> from Miettinen and Nurminen (1985) <doi:10.1002/sim.4780040211> and Gart and Nam (1988) <doi:10.2307/2531848>, and in Laud (2026, under review) for paired proportions. In each case, the same score produces hypothesis tests that are improved versions of the non-inferiority test for binomial RD and RR by Farrington and Manning (1990) <doi:10.1002/sim.4780091208>, or a generalisation of the McNemar test for paired data. The package also includes MOVER methods (Method Of Variance Estimates Recovery) for all contrasts, derived from the Newcombe method but with options to use equal-tailed intervals in place of the Wilson score method, and generalised for Bayesian applications incorporating prior information. So-called 'exact' methods for strictly conservative coverage are approximated using continuity adjustments, and the amount of adjustment can be selected to avoid over-conservative coverage. Also includes methods for stratified calculations (e.g. meta-analysis), either with fixed effect assumption (matching the CMH test) or incorporating stratum heterogeneity.
- Approximate Interval Estimation of the Ratio of Binomial Parameters: A Review and Corrections for Skewness
- Comparative analysis of two rates
- Equal-tailed confidence intervals for comparison of rates
- Test statistics and sample size formulae for comparative binomial trials with null hypothesis of non-zero risk difference or non-unity relative risk
This page was built for software: ratesci
