Scaling limits of a model for selection at two scales

DOI10.1088/1361-6544/AA5499MaRDI QIDQ5346537zbMATH OpenOpenAlexWikidataFDO

Authors Shishi Luo, Jonathan C. Mattingly

Publication date 24 May 2017

Published in Nonlinearity (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/1507.00397, http://europepmc.org/articles/pmc5580332

zbMATH Keywords

evolutionary dynamicsFleming-Viot processlimiting behaviorMarkov chainsscaling limits

Mathematics Subject Classification ID

Initial value problems for systems of nonlinear first-order PDEs (35F55) PDEs in connection with biology, chemistry and other natural sciences (35Q92) Integro-partial differential equations (35R09) Invariant measures for infinite-dimensional dissipative dynamical systems (37L40) Applications of continuous-time Markov processes on discrete state spaces (60J28) Superprocesses (60J68) Applications of Brownian motions and diffusion theory (population genetics, absorption problems, etc.) (60J70) Genetics and epigenetics (92D10) Problems related to evolution (92D15) Population dynamics (general) (92D25)

Abstract: The dynamics of a population undergoing selection is a central topic in evolutionary biology. This question is particularly intriguing in the case where selective forces act in opposing directions at two population scales. For example, a fast-replicating virus strain outcompetes slower-replicating strains at the within-host scale. However, if the fast-replicating strain causes host morbidity and is less frequently transmitted, it can be outcompeted by slower-replicating strains at the between-host scale. Here we consider a stochastic ball-and-urn process which models this type of phenomenon. We prove the weak convergence of this process under two natural scalings. The first scaling leads to a deterministic nonlinear integro-partial differential equation on the interval $[0,1]$ with dependence on a single parameter, $lambda$. We show that the fixed points of this differential equation are Beta distributions and that their stability depends on $lambda$ and the behavior of the initial data around $1$. The second scaling leads to a measure-valued Fleming-Viot process, an infinite dimensional stochastic process that is frequently associated with a population genetics.

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Cites work

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Cited in

(16)

• On the limit points of discrete selection dynamics
• Multilevel mutation-selection systems and set-valued duals
• Assortment and reciprocity mechanisms for promotion of cooperation in a model of multilevel selection
• Long-time behavior of a PDE replicator equation for multilevel selection in group-structured populations
• A PDE model for protocell evolution and the origin of chromosomes via multilevel selection
• Analysis of multilevel replicator dynamics for general two-strategy social dilemma
• Maintenance of diversity in a hierarchical host-parasite model with balancing selection and reinfection
• The replicator dynamics for multilevel selection in evolutionary games
• Group-level events are catalysts in the evolution of cooperation
• Multi-scale problem for a model of viral evolution with random mutations
• Two level natural selection with a quasi-stationarity approach
• The dynamics of casual groups can keep free-riders at bay
• Pattern formation in agent-based and PDE models for evolutionary games with payoff-driven motion
• Steady-state and dynamical behavior of a PDE model of multilevel selection with pairwise group-level competition
• Exploring the evolution of altruistic punishment with a PDE model of cultural multilevel selection
• Wright-Fisher kernels: from linear to non-linear dynamics, ergodicity and McKean-Vlasov scaling limits

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