Selecting effective siRNA sequences based on the self-organizing map and statistical techniques

DOI10.1016/J.COMPBIOLCHEM.2006.02.003MaRDI QIDQ2500373zbMATH OpenOpenAlexDBLPWikidataFDO

Authors Shigeru Takasaki, Yoshihiro Kawamura, Akihiko Konagaya

Publication date 23 August 2006

Published in Computational Biology and Chemistry (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.compbiolchem.2006.02.003

zbMATH Keywords

Gene-silencingRNA interferencesiRNA designSOM classificationStatistical significance

Mathematics Subject Classification ID

Computational methods for problems pertaining to biology (92-08) Biochemistry, molecular biology (92C40)

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(4)

• Using radial basis function networks and significance testing to select effective siRNA sequences
• Selecting effective siRNA target sequences by using Bayes' theorem
• siRNA design. Methods and protocols
• Computational Science – ICCS 2005

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