serodynamics

MaRDI QIDQ7377192CRANFDO

Authors Peter Teunis, Samuel Schildhauer, Kwan Ho Lee, Kristen Aiemjoy, Douglas Morrison

Last update 2 June 2026

Copyright license MIT license, File License

Software version identifier 0.1.0

Description

Implements Bayesian hierarchical models for estimating antibody kinetic parameters from longitudinal serological data. Fits two-phase within-host models capturing antibody rise, peak, and decay following pathogen infection, using 'JAGS' for posterior inference. Designed as the upstream companion to the 'serocalculator' package for end-to-end seroepidemiological analysis. Methods are described in Teunis and colleagues (2016) <doi:10.1016/j.epidem.2016.04.001> and Teunis and van Eijkeren (2020) <doi:10.1002/sim.8578>.

Cites work

• Estimation of seroconversion rates for infectious diseases: effects of age and noise
• Linking the seroresponse to infection to within-host heterogeneity in antibody production

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