Simultaneous reconstruction and segmentation for dynamic SPECT imaging

DOI10.1088/0266-5611/32/10/104002MaRDI QIDQ2832549zbMATH OpenOpenAlexFDO

Authors Martin Burger, Carolin Rossmanith, Xiaoqun Zhang

Publication date 11 November 2016

Published in Inverse Problems (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/1606.03852

zbMATH Keywords

Bergman distancedynamic SPECTimage reconstructionKullback-Leiblersparsitytotal variation

Mathematics Subject Classification ID

Radon transform (44A12) Numerical optimization and variational techniques (65K10) Biomedical imaging and signal processing (92C55)

Abstract: This work deals with the reconstruction of dynamic images that incorporate characteristic dynamics in certain subregions, as arising for the kinetics of many tracers in emission tomography (SPECT, PET). We make use of a basis function approach for the unknown tracer concentration by assuming that the region of interest can be divided into subregions with spatially constant concentration curves. Applying a regularized variational framework reminiscent of the Chan-Vese model for image segmentation we simultaneously reconstruct both the labelling functions of the subregions as well as the subconcentrations within each region. Our particular focus is on applications in SPECT with Poisson noise model, resulting in a Kullback-Leibler data fidelity in the variational approach. We present a detailed analysis of the proposed variational model and prove existence of minimizers as well as error estimates. The latter apply to a more general class of problems and generalize existing results in literature since we deal with a nonlinear forward operator and a nonquadratic data fidelity. A computational algorithm based on alternating minimization and splitting techniques is developed for the solution of the problem and tested on appropriately designed synthetic data sets. For those we compare the results to those of standard EM reconstructions and investigate the effects of Poisson noise in the data.

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(10)

• A Mumford-Shah-type approach to simultaneous reconstruction and segmentation for emission tomography problems with Poisson statistics
• Locally constrained mixture representation of dynamic imaging data from PET and MR studies
• Sparsest representations and approximations of an underdetermined linear system
• Dynamic SPECT reconstruction with temporal edge correlation
• Preface: Dynamic inverse problems: modelling-regularization-numerics
• Task adapted reconstruction for inverse problems
• Dynamic SPECT reconstruction from few projections: a sparsity enforced matrix factorization approach
• Joint reconstruction of dynamic PET activity and kinetic parametric images using total variation constrained dictionary sparse coding
• A Mumford-Shah level-set approach for the inversion and segmentation of SPECT/CT data
• GMM based simultaneous reconstruction and segmentation in X-ray CT application

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