Platypus

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Software:100283



CRANPlatypusMaRDI QIDQ100283

Single-Cell Immune Repertoire and Gene Expression Analysis

Alexander Yermanos

Last update: 21 February 2024

Software version identifier: 3.4.1, 3.2.3, 3.3.2, 3.3.5, 3.5.0


Copyright license: GNU General Public License, version 2.0

We present 'Platypus', an open-source software platform providing a user-friendly interface to investigate B-cell receptor and T-cell receptor repertoires from scSeq experiments. 'Platypus' provides a framework to automate and ease the analysis of single-cell immune repertoires while also incorporating transcriptional information involving unsupervised clustering, gene expression and gene ontology. This R version of 'Platypus' is part of the 'ePlatypus' ecosystem for computational analysis of immunogenomics data: Yermanos et al. (2021) <doi:10.1093/nargab/lqab023>, Cotet et al. (2023) <doi:10.1093/bioinformatics/btad553>.