PFIM
Population Fisher Information Matrix
France Mentré, Romain Leroux, Jérémy Seurat, Lucie Fayette
Last update: 24 November 2023
Software version identifier: 5.0, 6.0.1, 6.0, 6.0.2
Copyright license: GNU General Public License, version 3.0, GNU General Public License, version 2.0
Evaluate or optimize designs for nonlinear mixed effects models using the Fisher Information matrix. Methods used in the package refer to Mentré F, Mallet A, Baccar D (1997) <doi:10.1093/biomet/84.2.429>, Retout S, Comets E, Samson A, Mentré F (2007) <doi:10.1002/sim.2910>, Bazzoli C, Retout S, Mentré F (2009) <doi:10.1002/sim.3573>, Le Nagard H, Chao L, Tenaillon O (2011) <doi:10.1186/1471-2148-11-326>, Combes FP, Retout S, Frey N, Mentré F (2013) <doi:10.1007/s11095-013-1079-3> and Seurat J, Tang Y, Mentré F, Nguyen TT (2021) <doi:10.1016/j.cmpb.2021.106126>.
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- The emergence of complexity and restricted pleiotropy in adapting networks
- Prediction of Shrinkage of Individual Parameters Using the Bayesian Information Matrix in Non-Linear Mixed Effect Models with Evaluation in Pharmacokinetics
- Finding optimal design in nonlinear mixed effect models using multiplicative algorithms
