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Software:106192



CRANVEwaningMaRDI QIDQ106192FDOQ106192

Vaccine Efficacy Over Time

Marie Davidian, Shannon T. Holloway, A.a. Tsiatis

Last update: 13 December 2023

Copyright license: GNU General Public License, version 2.0

Software version identifier: 1.2, 1.1, 1.3

Implements methods for inference on potential waning of vaccine efficacy and for estimation of vaccine efficacy at a user-specified time after vaccination based on data from a randomized, double-blind, placebo-controlled vaccine trial in which participants may be unblinded and placebo subjects may be crossed over to the study vaccine. The methods also allow adjustment for possible confounding via inverse probability weighting through specification of models for the trial entry process, unblinding mechanisms, and the probability an unblinded placebo participant accepts study vaccine: Tsiatis, A. A. and Davidian, M. (2021) <arXiv:2102.13103> .





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