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Hill/Bliss Independence Model for Combination Vaccines

Last update: 24 August 2023

Copyright license: GNU General Public License, version 3.0

Software version identifier: 1.1, 0.9.5-1, 1.0.1, 1.0.2, 1.0.3, 1.1.2

Description

Calculate expected relative risk and proportion protected assuming normally distributed log10 transformed antibody dose for a several component vaccine. Uses Hill models for each component which are combined under Bliss independence. See Saul and Fay, 2007 <doi:10.1371/journal.pone.0000850>.

Cites work

Human Immunity and the Design of Multi-Component, Single Target Vaccines

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