snpsettest

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A Set-Based Association Test using GWAS Summary Statistics

Blanca Himes, Jaehyun Joo

Last update: 9 September 2023

Copyright license: GNU General Public License

Software version identifier: 0.1.1, 0.1.0, 0.1.2

The goal of 'snpsettest' is to provide simple tools that perform set-based association tests (e.g., gene-based association tests) using GWAS (genome-wide association study) summary statistics. A set-based association test in this package is based on the statistical model described in VEGAS (versatile gene-based association study), which combines the effects of a set of SNPs accounting for linkage disequilibrium between markers. This package uses a different approach from the original VEGAS implementation to compute set-level p values more efficiently, as described in <https://github.com/HimesGroup/snpsettest/wiki/Statistical-test-in-snpsettest>.





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