DIscBIO

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Software:127156



CRANDIscBIOMaRDI QIDQ127156

A User-Friendly Pipeline for Biomarker Discovery in Single-Cell Transcriptomics

Waldir Leoncio, Alvaro Köhn-Luque, Salim Ghannoum

Last update: 6 November 2023

Copyright license: MIT license, File License

Software version identifier: 1.2.0, 1.0.0, 1.0.1, 1.1.0, 1.2.1, 1.2.2

An open, multi-algorithmic pipeline for easy, fast and efficient analysis of cellular sub-populations and the molecular signatures that characterize them. The pipeline consists of four successive steps: data pre-processing, cellular clustering with pseudo-temporal ordering, defining differential expressed genes and biomarker identification. More details on Ghannoum et. al. (2021) <doi:10.3390/ijms22031399>. This package implements extensions of the work published by Ghannoum et. al. (2019) <doi:10.1101/700989>.





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