APackOfTheClones

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Visualization of Clonal Expansion for Single Cell Immune Profiles

Qile Yang

Last update: 13 January 2024

Copyright license: MIT license, File License

Software version identifier: 0.1.2, 0.1.3, 1.0.0

Description

Visualize clonal expansion via circle-packing. 'APackOfTheClones' extends 'scRepertoire' to produce a publication-ready visualization of clonal expansion at a single cell resolution, by representing expanded clones as differently sized circles. The method was originally implemented by Murray Christian and Ben Murrell in the following immunology study: Ma et al. (2021) <doi:10.1126/sciimmunol.abg6356>.

Cites work

• Single-cell analysis pinpoints distinct populations of cytotoxic CD4+T cells and an IL-10+CD109+TH2 cell population in nasal polyps

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