accrual

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Bayesian Accrual Prediction

Steve Simon, Rama Raghavan, Matthew S. Mayo, Cen Wu, Yu Jiang, Junhao Liu, Byron J. Gajewski

Last update: 26 November 2023

Copyright license: GNU General Public License, version 2.0

Software version identifier: 1.3, 1.0, 1.1, 1.2, 1.4

Source code repository: https://github.com/cran/accrual

Description

Participant recruitment for medical research is challenging. Slow accrual leads to delays in research. Accrual monitoring during the process of recruitment is critical. Researchers need reliable tools to manage the accrual rate. We developed a Bayesian method that integrates the researcher's experience with previous trials and data from the current study, providing reliable predictions on accrual rate for clinical studies. For more details and background on these methodologies, see the publications of Byron, Stephen and Susan (2008) <doi:10.1002/sim.3128>, and Yu et al. (2015) <doi:10.1002/sim.6359>. In this R package, Bayesian accrual prediction functions are presented, which can be easily used by statisticians and clinical researchers.

Cites work

• Predicting accrual in clinical trials with Bayesian posterior predictive distributions
• Modeling and validating Bayesian accrual models on clinical data and simulations using adaptive priors

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