crmPack
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Object-Oriented Implementation of CRM Designs
Thomas Jaki, Daniel Sabanes Bove, Wai Yin Yeung, Giuseppe Palermo
Last update: 4 February 2024
Copyright license: GNU General Public License, version 3.0, GNU General Public License, version 2.0
Software version identifier: 1.0.3, 0.1.5, 0.1.6, 0.1.7, 0.1.8, 0.1.9, 0.2.0, 0.2.1, 0.2.6, 0.2.7, 0.2.9, 1.0.0, 1.0.2, 1.0.3, 1.0.4, 1.0.5
Source code repository: https://github.com/cran/crmPack
Implements a wide range of model-based dose escalation designs, ranging from classical and modern continual reassessment methods (CRMs) based on dose-limiting toxicity endpoints to dual-endpoint designs taking into account a biomarker/efficacy outcome. The focus is on Bayesian inference, making it very easy to setup a new design with its own JAGS code. However, it is also possible to implement 3+3 designs for comparison or models with non-Bayesian estimation. The whole package is written in a modular form in the S4 class system, making it very flexible for adaptation to new models, escalation or stopping rules.
This page was built for software: crmPack
