OncoBayes2

swMATH36823CRANOncoBayes2MaRDI QIDQ52525

Bayesian Logistic Regression for Oncology Dose-Escalation Trials

Sebastian Weber, Lukas A. Widmer, Andrew Bean

Last update: 20 July 2023

Copyright license: GNU General Public License

Software version identifier: 0.8-8, 0.4-4, 0.5-3, 0.5-4, 0.5-8, 0.6-0, 0.6-3, 0.6-4, 0.6-5, 0.7-0, 0.8-1, 0.8-2, 0.8-4, 0.8-5, 0.8-6, 0.8-7, 0.8-9

Source code repository: https://github.com/cran/OncoBayes2

Description

Bayesian logistic regression model with optional EXchangeability-NonEXchangeability parameter modelling for flexible borrowing from historical or concurrent data-sources. The safety model can guide dose-escalation decisions for adaptive oncology Phase I dose-escalation trials which involve an arbitrary number of drugs. Please refer to Neuenschwander et al. (2008) <doi:10.1002/sim.3230> and Neuenschwander et al. (2016) <doi:10.1080/19466315.2016.1174149> for details on the methodology.

Cites work

• Critical aspects of the Bayesian approach to phase I cancer trials
• On the Use of Co-Data in Clinical Trials

This page was built for software: OncoBayes2