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Confirmatory Adaptive Clinical Trial Design and Analysis
Gernot Wassmer, Friedrich Pahlke
Last update: 25 January 2024
Copyright license: GNU Lesser General Public License, version 3.0
Software version identifier: 3.3.4, 1.0.0, 2.0.0, 2.0.1, 2.0.2, 2.0.3, 2.0.4, 2.0.5, 2.0.6, 3.0.0, 3.0.1, 3.0.2, 3.0.3, 3.0.4, 3.1.0, 3.1.1, 3.2.0, 3.2.1, 3.2.2, 3.2.3, 3.3.0, 3.3.1, 3.3.2, 3.3.3, 3.4.0, 3.5.0
Official website: https://cran.r-project.org/web/packages/rpact/index.html
Source code repository: https://github.com/cran/rpact
Design and analysis of confirmatory adaptive clinical trials with continuous, binary, and survival endpoints according to the methods described in the monograph by Wassmer and Brannath (2016) <doi:10.1007/978-3-319-32562-0>. This includes classical group sequential as well as multi-stage adaptive hypotheses tests that are based on the combination testing principle.
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