nlmixr2est
Nonlinear Mixed Effects Models in Population PK/PD, Estimation Routines
Matthew L. Fidler, Yuan Xiong, Rik C Schoemaker, Justin J Wilkins, Wenping Wang, Vipul Mann, Richard Hooijmaijers
Last update: 31 January 2024
Software version identifier: 2.1.4, 2.1.5, 2.1.6, 2.0.6, 2.0.7, 2.0.8, 2.1.0, 2.1.1, 2.1.2, 2.1.3, 2.1.6, 2.1.7, 2.1.8, 2.2.0, 2.2.1
Copyright license: GNU General Public License
Fit and compare nonlinear mixed-effects models in differential equations with flexible dosing information commonly seen in pharmacokinetics and pharmacodynamics (Almquist, Leander, and Jirstrand 2015 <doi:10.1007/s10928-015-9409-1>). Differential equation solving is by compiled C code provided in the 'rxode2' package (Wang, Hallow, and James 2015 <doi:10.1002/psp4.12052>).
