insane

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Software:58926



CRANinsaneMaRDI QIDQ58926

INsulin Secretion ANalysEr

Mickaël Canouil

Last update: 14 November 2023

Copyright license: MIT license, File License

Software version identifier: 1.0.2, 0.1.0, 1.0.0, 1.0.1, 1.0.3

A user-friendly interface, using Shiny, to analyse glucose-stimulated insulin secretion (GSIS) assays in pancreatic beta cells or islets. The package allows the user to import several sets of experiments from different spreadsheets and to perform subsequent steps: summarise in a tidy format, visualise data quality and compare experimental conditions without omitting to account for technical confounders such as the date of the experiment or the technician. Together, insane is a comprehensive method that optimises pre-processing and analyses of GSIS experiments in a friendly-user interface. The Shiny App was initially designed for EndoC-betaH1 cell line following method described in Ndiaye et al., 2017 (<doi:10.1016/j.molmet.2017.03.011>).





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