TrialEmulation

Causal Analysis of Observational Time-to-Event Data

Li Su, Roonak Rezvani, Isaac Gravestock

Last update: 24 January 2024

Copyright license: Apache License

Software version identifier: 0.0.3.2, 0.0.3.8

Implements target trial emulation methods to apply randomized clinical trial design and analysis in an observational setting. Using marginal structural models, it can estimate intention-to-treat and per-protocol effects in emulated trials using electronic health records. A description and application of the method can be found in Danaei et al (2013) <doi:10.1177/0962280211403603>.

Cites work

Observational data for comparative effectiveness research: An emulation of randomised trials of statins and primary prevention of coronary heart disease

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