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CRANBPrinStratTTEMaRDI QIDQ5978738FDOQ5978738

Causal Effects in Principal Strata Defined by Antidrug Antibodies

Christian Stock, Emma Torrini

Last update: 20 December 2023

Copyright license: GNU General Public License

Software version identifier: 0.0.2

Description

Bayesian models to estimate causal effects of biological treatments on time-to-event endpoints in clinical trials with principal strata defined by the occurrence of antidrug antibodies. The methodology is based on Frangakis and Rubin (2002) <doi:10.1111/j.0006-341x.2002.00021.x> and Imbens and Rubin (1997) <doi:10.1214/aos/1034276631>, and intended to be applied to a specific time-to-event setting.

Cites work

• Principal Stratification in Causal Inference
• Bayesian inference for causal effects in randomized experiments with noncompliance

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