TaxaNorm

CRANTaxaNormMaRDI QIDQ5979016FDOQ5979016

Feature-Wise Normalization for Microbiome Sequencing Data

Ziyue Wang, Alison Motsinger-Reif, Shanshan Zhao, Dillon Lloyd

Last update: 12 December 2023

Copyright license: GNU General Public License, version 3.0

Software version identifier: 2.4

Description

A novel feature-wise normalization method based on a zero-inflated negative binomial model. This method assumes that the effects of sequencing depth vary for each taxon on their mean and also incorporates a rational link of zero probability and taxon dispersion as a function of sequencing depth. Ziyue Wang, Dillon Lloyd, Shanshan Zhao, Alison Motsinger-Reif (2023) <doi:10.1101/2023.10.31.563648>.

Cites work

• TaxaNorm: a novel taxa-specific normalization approach for microbiome data

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