FlexVarJM

Estimate Joint Models with Subject-Specific Variance

Léonie Courcoul, Antoine Barbieri, Hélène Jacqmin-Gadda

Last update: 20 November 2023

Software version identifier: 0.1.0

Copyright license: GNU General Public License

Estimation of mixed models including a subject-specific variance which can be time and covariate dependent. In the joint model framework, the package handles left truncation and allows a flexible dependence structure between the competing events and the longitudinal marker. The estimation is performed under the frequentist framework, using the Marquardt-Levenberg algorithm. (Courcoul, Tzourio, Woodward, Barbieri, Jacqmin-Gadda (2023) <arXiv:2306.16785>).

Cites work

A location-scale joint model for studying the link between the time-dependent subject-specific variability of blood pressure and competing events