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Software:5981218



CRANLDAcoopMaRDI QIDQ5981218FDOQ5981218

Analysis of Data from Limiting Dilution Assay (LDA) with or without Cellular Cooperation

Benedek Danko, Daniel Samaga, Horst Zitzelsberger, Kirsten Lauber, Nikko Brix

Last update: 9 October 2023

Copyright license: GNU General Public License, version 3.0

Software version identifier: 0.1.1

Cellular cooperation compromises the established method ofcalculating clonogenic activity from limiting dilution assay (LDA) data.This tool provides functions that enable robust analysis in presence orabsence of cellular cooperation. The implemented method incorporates thesame cooperativity module to model the non-linearity associated withcellular cooperation as known from the colony formation assay (Brix et al.(2021) <doi:10.1038/s41596-021-00615-0>: "Analysis of clonogenic growth invitro." Nature protocols).





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