LDAcoop
Analysis of Data from Limiting Dilution Assay (LDA) with or without Cellular Cooperation
Kirsten Lauber, Nikko Brix, Daniel Samaga, Horst Zitzelsberger, Benedek Danko
Last update: 9 October 2023
Software version identifier: 0.1.1
Copyright license: GNU General Public License, version 3.0
Cellular cooperation compromises the established method ofcalculating clonogenic activity from limiting dilution assay (LDA) data.This tool provides functions that enable robust analysis in presence orabsence of cellular cooperation. The implemented method incorporates thesame cooperativity module to model the non-linearity associated withcellular cooperation as known from the colony formation assay (Brix et al.(2021) <doi:10.1038/s41596-021-00615-0>: "Analysis of clonogenic growth invitro." Nature protocols).
