geneSLOPE
CRANgeneSLOPEMaRDI QIDQ5983050FDOQ5983050
Genome-Wide Association Study with SLOPE
Chiara Sabatti, Christine Peterson, Piotr Sobczyk, Damian Brzyski, Malgorzata Bogdan, Emmanuel J. Candes
Last update: 16 August 2023
Copyright license: GNU General Public License, version 3.0
Software version identifier: 0.36.6, 0.37.0, 0.38.2
Genome-wide association study (GWAS) performed with SLOPE, short for Sorted L-One Penalized Estimation, a method for estimating the vector of coefficients in a linear model. In the first step of GWAS, single nucleotide polymorphisms (SNPs) are clumped according to their correlations and distances. Then, SLOPE is performed on the data where each clump has one representative. Malgorzata Bogdan, Ewout van den Berg, Chiara Sabatti, Weijie Su and Emmanuel Candes (2014) "SLOPE - Adaptive Variable Selection via Convex Optimization" <arXiv:1407.3824>.
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