lit

CRANlitMaRDI QIDQ5983082FDOQ5983082

Latent Interaction Testing for Genome-Wide Studies

Andrew Bass, Michael Epstein

Last update: 15 August 2023

Copyright license: GNU Library General Public License, version 2.0, GNU Lesser General Public License, version 2.1, GNU Lesser General Public License, version 3.0

Software version identifier: 1.0.0

Description

Identifying latent genetic interactions in genome-wide association studies using the Latent Interaction Testing (LIT) framework. LIT is a flexible kernel-based approach that leverages information across multiple traits to detect latent genetic interactions without specifying or observing the interacting variable (e.g., environment). LIT accepts standard PLINK files as inputs to analyze large genome-wide association studies.

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