STAREG

An Empirical Bayes Approach for Replicability Analysis Across Two Studies

Yan Li, Rui Chen, Xiang Zhou, Xianyang Zhang, Hongyuan Cao

Last update: 15 August 2023

Copyright license: GNU General Public License, version 3.0

Software version identifier: 1.0.0, 1.0.1, 1.0.2, 1.0.3

Description

A robust and powerful empirical Bayesian approach is developed for replicability analysis of two large-scale experimental studies. The method controls the false discovery rate by using the joint local false discovery rate based on the replicability null as the test statistic. An EM algorithm combined with a shape constraint nonparametric method is used to estimate unknown parameters and functions. [Li, Y. et al., (2023), <https://www.biorxiv.org/content/10.1101/2023.05.30.542607v1>].

This page was built for software: STAREG