funkycells

Functional Data Analysis for Multiplexed Cell Images

Jeremy Vanderdoes, Gregory Rice, Jack D. Hywood

Last update: 9 August 2023

Software version identifier: 1.1.1

Copyright license: GNU General Public License

Compare variables of interest between (potentially large numbers of) spatial interactions and meta-variables. Spatial variables are summarized using K, or other, functions, and projected for use in a modified random forest model. The model allows comparison of functional and non-functional variables to each other and to noise, giving statistical significance to the results. Included are preparation, modeling, and interpreting tools along with example datasets, as described in VanderDoes et al., (2023) <doi:10.1101/2023.07.18.549619>.

Cites work

Using random forests to uncover the predictive power of distance–varying cell interactions in tumor microenvironments