OptimalGoldstandardDesigns

CRANOptimalGoldstandardDesignsMaRDI QIDQ66450

Design Parameter Optimization for Gold-Standard Non-Inferiority Trials

Jan Meis

Last update: 11 September 2023

Copyright license: GNU General Public License

Software version identifier: 1.0.0, 1.0.1

Description

Methods to calculate optimal design parameters for one- and two-stage three-arm group-sequential gold-standard non-inferiority trial designs with or without binding or nonbinding futility boundaries, as described in Meis et al. (2023) <doi:10.1002/sim.9630>.

Cites work

• Optimization of the two‐stage group sequential three‐arm gold‐standard design for non‐inferiority trials

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