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CRANcaratMaRDI QIDQ86798FDOQ86798

Covariate-Adaptive Randomization for Clinical Trials

Xiaoqing Ye, Feifang Hu, Wei Ma, Fuyi Tu

Last update: 5 September 2023

Copyright license: GNU General Public License, version 3.0, GNU General Public License, version 2.0

Software version identifier: 2.1.0, 2.2.0, 0.1.0, 0.1.1, 1.0, 1.1, 1.2, 1.3, 1.4, 1.5, 2.0.1, 2.0.2, 2.0, 2.2.1

Provides functions and command-line user interface to generate allocation sequence by covariate-adaptive randomization for clinical trials. The package currently supports six covariate-adaptive randomization procedures. Three hypothesis testing methods that are valid and robust under covariate-adaptive randomization are also available in the package to facilitate the inference for treatment effect under the included randomization procedures. Additionally, the package provides comprehensive and efficient tools to allow one to evaluate and compare the performance of randomization procedures and tests based on various criteria. See Ma W, Ye X, Tu F, and Hu F (2023) <doi:10.18637/jss.v107.i02> for details.





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