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Treatment Allocation in Clinical Trials by the Maximal Procedure

Ignacio López-de-Ullibarri

Last update: 15 January 2024

Copyright license: GNU General Public License, version 3.0, GNU General Public License, version 2.0

Software version identifier: 0.1-5, 0.1-3, 0.1-4, 0.1-6

Description

Performs treatment allocation in two-arm clinical trials by the maximal procedure described by Berger et al. (2003) <doi:10.1002/sim.1538>. To that end, the algorithm provided by Salama et al. (2008) <doi:10.1002/sim.3014> is implemented.

Cites work

• Minimizing predictability while retaining balance through the use of less restrictive randomization procedures
• Efficient generation of constrained block allocation sequences

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