toxEval

Exploring Biological Relevance of Environmental Chemistry Observations

Gerald T. Ankley, Steven R. Corsi, Daniel L. Villeneuve, Brett R. Blackwell, Laura A. Decicco

Last update: 8 February 2024

Copyright license: CC0

Software version identifier: 1.3.0, 1.0.3, 1.0.4, 1.1.0, 1.2.0, 1.3.1, 1.3.2

Description

Data analysis package for estimating potential biological effects from chemical concentrations in environmental samples. Included are a set of functions to analyze, visualize, and organize measured concentration data as it relates to user-selected chemical-biological interaction benchmark data such as water quality criteria. The intent of these analyses is to develop a better understanding of the potential biological relevance of environmental chemistry data. Results can be used to prioritize which chemicals at which sites may be of greatest concern. These methods are meant to be used as a screening technique to predict potential for biological influence from chemicals that ultimately need to be validated with direct biological assays. A description of the analysis can be found in Blackwell (2017) <doi:10.1021/acs.est.7b01613>.

Cites work

An “EAR” on Environmental Surveillance and Monitoring: A Case Study on the Use of Exposure–Activity Ratios (EARs) to Prioritize Sites, Chemicals, and Bioactivities of Concern in Great Lakes Waters

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