GRSxE

Testing Gene-Environment Interactions Through Genetic Risk Scores

Last update: 30 October 2023

Copyright license: MIT license, File License

Software version identifier: 1.0.0, 1.0.1

Statistical testing procedures for detecting GxE (gene-environment) interactions. The main focus lies on GRSxE interaction tests that aim at detecting GxE interactions through GRS (genetic risk scores). Moreover, a novel testing procedure based on bagging and OOB (out-of-bag) predictions is implemented for incorporating all available observations at both GRS construction and GxE testing (Lau et al., 2023, <doi:10.1038/s41598-023-28172-4>).

Cites work

Efficient gene–environment interaction testing through bootstrap aggregating

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