DrugSim2DR

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Software:90013



CRANDrugSim2DRMaRDI QIDQ90013

Predict Drug Functional Similarity to Drug Repurposing

Junwei Han, Ji Li, Jiashuo Wu

Last update: 10 August 2023

Software version identifier: 0.1.0, 0.1.1


Copyright license: GNU General Public License, version 3.0, GNU General Public License, version 2.0

A systematic biology tool was developed to repurpose drugs via a drug-drug functional similarity network. 'DrugSim2DR' first predict drug-drug functional similarity in the context of specific disease, and then using the similarity constructed a weighted drug similarity network. Finally, it used a network propagation algorithm on the network to identify drugs with significant target abnormalities as candidate drugs.