LTFHPlus
type: Item
instance of: R package
description: Implementation of LT-FH++, an extension of the liability threshold family history (LT-FH) model. LT-FH++ uses a Gibbs sampler for sampling from the truncated multivariate normal distribution and allows for flexible family structures. LT-FH++ was first described in Pedersen, Emil M., et al. (2022) <https://pure.au.dk/ws/portalfiles/portal/353346245/> as an extension to LT-FH with more flexible family structures, and again as the age-dependent liability threshold (ADuLT) model Pedersen, Emil M., et al. (2023) <https://www.nature.com/articles/s41467-023-41210-z> as an alternative to traditional time-to-event genome-wide association studies, where family history was not considered.
last update: 2024-02-12T00:00:00Z
software version identifier: 2.1.1
author: Emil Michael Pedersen
author: Florian Privé
author: Jette Steinbach
maintained by: Emil Michael Pedersen
copyright license: GNU General Public License, version 3.0
imports: batchmeans
imports: dplyr
imports: future.apply
imports: future
imports: purrr
imports: Rcpp
imports: rlang
imports: stats
imports: stringr
imports: tibble
imports: tmvtnorm
imports: tidyselect
imports: igraph
imports: xgboost
imports: tidyr
CRAN project: LTFHPlus
programmed in: R
MaRDI profile type: MaRDI software profile
description: Implementation of LT-FH++