sigminer (Q68655)

From MaRDI portal
Extract, Analyze and Visualize Mutational Signatures for Genomic Variations
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sigminer
Extract, Analyze and Visualize Mutational Signatures for Genomic Variations

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    2.2.0
    6 April 2023
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    0.1.9
    25 April 2019
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    0.1.11
    7 May 2019
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    1.0.0
    31 March 2020
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    1.0.3
    1 May 2020
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    1.0.5
    14 May 2020
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    1.0.6
    1 June 2020
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    1.0.7
    17 June 2020
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    1.0.13
    27 August 2020
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    1.0.16
    12 September 2020
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    1.0.19
    28 September 2020
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    1.1.0
    11 November 2020
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    1.2.1
    8 January 2021
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    1.2.4
    31 January 2021
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    1.2.5
    20 February 2021
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    2.0.0
    1 April 2021
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    2.0.1
    19 May 2021
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    2.0.2
    17 June 2021
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    2.0.3
    19 July 2021
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    2.0.4
    3 August 2021
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    2.0.5
    3 September 2021
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    2.1.0
    22 September 2021
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    2.1.1
    29 October 2021
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    2.1.2
    15 December 2021
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    2.1.3
    10 March 2022
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    2.1.4
    26 April 2022
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    2.1.5
    30 June 2022
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    2.1.6
    9 August 2022
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    2.1.7
    31 August 2022
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    2.1.8
    20 October 2022
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    2.1.9
    9 November 2022
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    2.2.2
    21 August 2023
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    2.3.0
    12 December 2023
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    12 December 2023
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    Genomic alterations including single nucleotide substitution, copy number alteration, etc. are the major force for cancer initialization and development. Due to the specificity of molecular lesions caused by genomic alterations, we can generate characteristic alteration spectra, called 'signature' (Wang, Shixiang, et al. (2021) <doi:10.1371/journal.pgen.1009557> & Alexandrov, Ludmil B., et al. (2020) <doi:10.1038/s41586-020-1943-3> & Steele Christopher D., et al. (2022) <doi:10.1038/s41586-022-04738-6>). This package helps users to extract, analyze and visualize signatures from genomic alteration records, thus providing new insight into cancer study.
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