Subgroup-specific dose finding for phase I-II trials using Bayesian clustering

DOI10.1002/SIM.9410MaRDI QIDQ6628623zbMATH OpenFDO

Authors Alexandra Curtis, Smith, Brian J., Andrew G. Chapple

Publication date 29 October 2024

Published in Statistics in Medicine (Search for Journal in Brave)

Copyright license Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International

Full work available at URL https://doi.org/10.1002/SIM.9410

zbMATH Keywords

Bayesian model averagingdose-finding clinical trialspike-and-slab priorsubgroup

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Cites work

• Bayesian hierarchical classification and information sharing for clinical trials with subgroups and binary outcomes
• Continual reassessment method for ordered groups
• Dose-Finding Based on Efficacy-Toxicity Trade-Offs
• Julia: a fresh approach to numerical computing

Cited in

(2)

• Dose individualization for phase I cancer trials with broadened eligibility
• Phase I/II design for selecting subgroup-specific optimal biological doses for prespecified subgroups

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