tLagInterim

MaRDI QIDQ100019CRANFDO

Authors Shannon T. Holloway, Marie Davidian, Anastasios Tsiatis

Last update 4 May 2025

Copyright license GNU General Public License, version 2.0

Software version identifier 1.0, PACKAGES.rds, 1.1

Description

Implements inverse and augmented inverse probability weighted estimators for common treatment effect parameters at an interim analysis with time-lagged outcome that may not be available for all enrolled subjects. Produces estimators, standard errors, and information that can be used to compute stopping boundaries using software that assumes that the estimators/test statistics have independent increments. Tsiatis, A. A. and Davidian, M., (2022) <doi:10.1002/sim.9580> .

Cites work

• Group sequential methods for interim monitoring of randomized clinical trials with time-lagged outcome

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