linear parameter estimation (uni uni reaction without product - Eadie Hofstee model - irreversibility assumption)

computational task	linear task

Available identifiers

linear fit to determine the limiting reaction rate and michaelis constant, named after Barend Hendrik Jan Hofstee, George Sharpe Eadie

Eadie Hofstee equation (uni uni reaction without product - irreversibility assumption)	$v_{0} = V_{m a x, f} - K_{S} \frac{v_{0}}{c_{S}}$
	$K_{S}$ represents Michaelis constant substrate (uni uni reaction - irreversibility assumption)
	$V_{m a x, f}$ represents limiting reaction rate (uni uni reaction - forward)
	$c_{S}$ represents substrate concentration
	$v_{0}$ represents initial reaction rate

Michaelis constant substrate (uni uni reaction - irreversibility assumption)	$K_{S} \equiv \frac{k_{2}}{k_{1}}$	output
	$k_{1}$ represents reaction rate constant
	$k_{2}$ represents reaction rate constant
	$K_{S}$ represents Michaelis constant substrate (uni uni reaction - irreversibility assumption)

initial reaction rate
limiting reaction rate (uni uni reaction - forward)	$V_{m a x, f} \equiv k_{2} c_{E_{0}}$	output
	$c_{E_{0}}$ represents enzyme concentration
	$k_{2}$ represents reaction rate constant
	$V_{m a x, f}$ represents limiting reaction rate (uni uni reaction - forward)

substrate concentration

Item	Property
linear parameter estimation of enzyme kinetics	specialized by
nonlinear parameter estimation (uni uni reaction without product - Michaelis Menten model - irreversibility assumption)	linearized by
uni uni reaction (Eadie Hofstee model without product - irreversibility assumption)	used by

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