nonlinear parameter estimation (uni uni reaction without product - Michaelis Menten model - steady state assumption)

computational task	nonlinear task

Available identifiers

nonlinear fit to determine the limiting reaction rate and michaelis constant, named after Leonor Michaelis, Maud Menten

Michaelis Menten equation (uni uni reaction without product - steady state assumption)	$v_{0} = \frac{V_{m a x, f} c_{S}}{K_{S} + c_{S}}$
	$K_{S}$ represents Michaelis constant substrate (uni uni reaction - steady state assumption)
	$V_{m a x, f}$ represents limiting reaction rate (uni uni reaction - forward)
	$c_{S}$ represents substrate concentration
	$v_{0}$ represents initial reaction rate

Michaelis constant substrate (uni uni reaction - steady state assumption)	$K_{S} \equiv \frac{k_{- 1} + k_{2}}{k_{1}}$	output
	$k_{- 1}$ represents reaction rate constant
	$k_{1}$ represents reaction rate constant
	$k_{2}$ represents reaction rate constant
	$K_{S}$ represents Michaelis constant substrate (uni uni reaction - steady state assumption)

initial reaction rate
limiting reaction rate (uni uni reaction - forward)	$V_{m a x, f} \equiv k_{2} c_{E_{0}}$	output
	$c_{E_{0}}$ represents enzyme concentration
	$k_{2}$ represents reaction rate constant
	$V_{m a x, f}$ represents limiting reaction rate (uni uni reaction - forward)

substrate concentration

Item	Property
nonlinear parameter estimation of enzyme kinetics	specialized by
uni uni reaction (Michaelis Menten model without product - steady state assumption)	used by

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