linear parameter estimation (uni uni reaction without product - Hanes Woolf model - rapid equilibrium assumption)

computational task	linear task

Available identifiers

linear fit to determine the limiting reaction rate and michaelis constant, named after Barnet Woolf, Charles Samuel Hanes

Hanes Woolf equation (uni uni reaction without product - rapid equilibrium assumption)	$\frac{c_{S}}{v_{0}} = \frac{1}{V_{m a x, f}} c_{S} + \frac{K_{S}}{V_{m a x, f}}$
	$K_{S}$ represents Michaelis constant substrate (uni uni reaction - rapid equilibrium assumption)
	$V_{m a x, f}$ represents limiting reaction rate (uni uni reaction - forward)
	$c_{S}$ represents substrate concentration
	$v_{0}$ represents initial reaction rate

Michaelis constant substrate (uni uni reaction - rapid equilibrium assumption)	$K_{S} \equiv \frac{k_{- 1}}{k_{1}}$	output
	$k_{- 1}$ represents reaction rate constant
	$k_{1}$ represents reaction rate constant
	$K_{S}$ represents Michaelis constant substrate (uni uni reaction - rapid equilibrium assumption)

initial reaction rate
limiting reaction rate (uni uni reaction - forward)	$V_{m a x, f} \equiv k_{2} c_{E_{0}}$	output
	$c_{E_{0}}$ represents enzyme concentration
	$k_{2}$ represents reaction rate constant
	$V_{m a x, f}$ represents limiting reaction rate (uni uni reaction - forward)

substrate concentration

Item	Property
linear parameter estimation of enzyme kinetics	specialized by
nonlinear parameter estimation (uni uni reaction without product - Michaelis Menten model - rapid equilibrium assumption)	linearized by
uni uni reaction (Hanes Woolf model without product - rapid equilibrium assumption)	used by

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