The analysis of sequential clinical trials

DOI10.1093/BIOMET/66.3.443MaRDI QIDQ3851473zbMATH OpenOpenAlexFDO

Authors

Publication date 1979

Published in Biometrika (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1093/biomet/66.3.443

zbMATH Keywords

clinical trialconfidence intervalestimationlarge sample testlog rank testmodified Wilcoxon testsequential analysissignificance level

Mathematics Subject Classification ID

Sequential statistical analysis (62L10) Applications of statistics to biology and medical sciences; meta analysis (62P10)

Cited in

(6)

• A remark on the size of \(\pi_q(S^n)\)
• Group sequential designs for one-sided and two-sided hypothesis testing with provision for early stopping in favor of the null hypothesis
• Approximating boundary crosing probabilities with applications to sequential tests
• Use of the randomization distribution in the analysis of sequential clinical trials
• An overview of sequential methods and their application in clinical trials
• The STRAND chart: a survival time control chart

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