Unsupervised learning of pharmacokinetic responses

DOI10.1007/S00180-016-0707-XMaRDI QIDQ2358927zbMATH OpenOpenAlexDBLPWikidataFDO

Authors Elson Tomás, Susana Vinga, Alexandra M. Carvalho

Publication date 27 June 2017

Published in Computational Statistics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/s00180-016-0707-x

zbMATH Keywords

clusteringexpectation-maximizationone-compartment model

Mathematics Subject Classification ID

Classification and discrimination; cluster analysis (statistical aspects) (62H30) Applications of statistics to biology and medical sciences; meta analysis (62P10) Learning and adaptive systems in artificial intelligence (68T05)

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Cites work

• scientific article; zbMATH DE number 3567782 (Why is no real title available?)
• A Joint Model for Nonlinear Mixed-Effects Models With Censoring and Covariates Measured With Error, With Application to AIDS Studies
• An EM Algorithm for Nonlinear Random Effects Models
• Convergence of a stochastic approximation version of the EM algorithm
• Coordinate descent algorithms
• Discriminative learning of Bayesian networks via factorized conditional log-likelihood
• Efficiency of coordinate descent methods on huge-scale optimization problems
• Exact and Approximate Inferences for Nonlinear Mixed-Effects Models With Missing Covariates
• Hybrid learning of Bayesian multinets for binary classification
• Maximum likelihood estimation in nonlinear mixed effects models
• Newton-Raphson and EM Algorithms for Linear Mixed-Effects Models for Repeated-Measures Data
• Nonlinear nonparametric mixed-effects models for unsupervised classification
• Stochastic complexity in learning

Cited in

(1)

• Learning pharmacokinetic models for in vivo glucocorticoid activation

Describes a project that uses

Uses Software

• NONMEM

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