Using win odds to improve commit-to-phase-3 decision-making in oncology

DOI10.1002/SIM.70024MaRDI QIDQ6966154zbMATH OpenFDO

Authors Benjamin F. Hartley, Thomas Drury, Brian Di Pace, Helen Zhou, Tai-Tsang Chen, Inna Perevozskaya

Publication date 30 June 2025

Published in Statistics in Medicine (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1002/SIM.70024

zbMATH Keywords

multi-state modelphase 2 clinical trialsquantitative decision makingsurrogate endpointswin statistics

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Cites work

• A multistate model for early decision-making in oncology
• Estimating the Relative Risk with Censored Data
• Estimation of the average hazard ratio
• scientific article; zbMATH DE number 3240796 (Why is no real title available?)
• Joint modeling of progression-free and overall survival and computation of correlation measures
• Multistate models as a framework for estimand specification in clinical trials of complex processes
• Multistate Models for the Analysis of Life History Data
• On the win-ratio statistic in clinical trials with multiple types of event
• The Efficiency of Cox's Likelihood Function for Censored Data
• Win odds: an adaptation of the win ratio to include ties

Cited in

(1)

• Generalized win-odds regression models for composite endpoints

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