valytics
Provides statistical methods for analytical method comparison and validation studies. Implements Bland-Altman analysis for assessing agreement between measurement methods (Bland & Altman (1986) <doi:10.1016/S0140-6736(86)90837-8>), Passing-Bablok regression for non-parametric method comparison (Passing & Bablok (1983) <doi:10.1515/cclm.1983.21.11.709>), and Deming regression accounting for measurement error in both variables (Linnet (1993) <doi:10.1093/clinchem/39.3.424>). Also includes tools for setting quality goals based on biological variation (Fraser & Petersen (1993) <doi:10.1093/clinchem/39.7.1447>) and calculating Six Sigma metrics, precision experiments with variance component analysis, precision profiles for functional sensitivity estimation (Kroll & Emancipator (1993) <https://pubmed.ncbi.nlm.nih.gov/8448849/>). Commonly used in clinical laboratory method validation. Provides publication-ready plots and comprehensive statistical summaries.
- A New Biometrical Procedure for Testing the Equality of Measurements from Two Different Analytical Methods. Application of linear regression procedures for method comparison studies in Clinical Chemistry, Part I
- Desirable standards for laboratory tests if they are to fulfill medical needs
- Evaluation of regression procedures for methods comparison studies
- STATISTICAL METHODS FOR ASSESSING AGREEMENT BETWEEN TWO METHODS OF CLINICAL MEASUREMENT
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