XYomics

MaRDI QIDQ7374004CRANFDO

Authors Enrico Glaab, Sophie LE BARS, Mohamed Soudy

Last update 30 July 2026

Copyright license MIT license, File License

Software version identifier PACKAGES.rds, 0.1.1, 0.1.2, 0.1.3, 0.1.4, 0.1.5

Description

Tools to analyze sex differences in omics data for complex diseases. It includes functions for differential expression analysis using the 'limma' method <doi:10.1093/nar/gkv007>, interaction testing between sex and disease, pathway enrichment with 'clusterProfiler' <doi:10.1089/omi.2011.0118>, and gene regulatory network (GRN) construction and analysis using 'igraph'. The package enables a reproducible workflow from raw data processing to biological interpretation.

Cites work

• clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters
• limma powers differential expression analyses for RNA-sequencing and microarray studies

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